Adverse effects associated with COVID-19 vaccines in officials and students of the Faculty of Chemical Sciences of UNA, year 2021

Authors

DOI:

https://doi.org/10.32480/rscp.2023.28.1.71

Keywords:

COVID-19, SARS-COV-2, vaccination, adverse effects

Abstract

COVID-19 is an infectious disease caused by the SARS-COV-2 virus. It was declared a global public health emergency and vaccination was raised as the best tool to combat it. People who receive a vaccine often experience mild or moderate side effects. In this study, the frequency of adverse effects associated with vaccines against COVID-19 in employees and students of the Facultad de Ciencias Químcias-UNA, during the year 2021 was determined. For this, an analytical cross-sectional observational study was conducted. The accessible population were the employees and students of the FCQ-UNA, of both sexes, vaccinated with the first two doses of the available vaccines against COVID-19, and who have agreed to take part in the study by giving their informed consent. Data collection was performed by applying a survey using Google Forms using non-probabilistic convenience sampling by conglomerates. The following were analyzed: sex, age, underlying diseases, type of vaccine received, clinical manifestations presented after the application of the vaccines, and the time of onset of symptoms. 147 people met the inclusion criteria; 85% were female; 68.7% were between 20 and 29 years old; 60.5% received the Pfizer vaccine; 71.4% had a history of COVID-19 and 78.2% had no underlying disease. In addition, 60.5% of the study population presented symptoms after the first dose, and 61.2% after the second dose. The onset of symptoms was mainly between 8 and 12 hours after vaccination, both for the first and second doses. It is concluded that most of the targeted population presented mild side effects, attributable to the vaccines.

Metrics

Metrics Loading ...

Downloads

Download data is not yet available.

References

(1) Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. NEJM. 2020;382(8):727-33.

(2) Hao W, Li M, Huang X. First atypical case of 2019 novel coronavirus in Yan’an, China. Clin Microbiol. Infect. 2020;26(7):952-3.

(3) Yang T, Wang YC, Shen CF, Cheng CM. Point-of-care RNA-based diagnostic device for COVID-19. Diagnostics. 2020;10(3):165.

(4) Phelan AL, Katz R, Gostin LO. The novel coronavirus originating in Wuhan, China: Challenges for Global Health Governance. JAMA. 2020;323(8):709-10.

(5) Jiang S, Shi Z, Shu Y, Song J, Gao GF, Tan W, et al. A distinct name is needed for the new coronavirus. The Lancet. 2020;395(10228):949.

(6) Lui RN, Wong SH, Sánchez-Luna SA, Pellino G, Bollipo S, Wong MY, et al. Overview of guidance for endoscopy during the coronavirus disease 2019 pandemic. J. Gastroenterol. Hepatol. 2020;35(5):749-59.

(7) Zuo Mingzhang HY. Expert recommendations for tracheal intubation in critically Ill patients with noval coronavirus disease 2019. Chin. Med. Sci. J. 2020;35(2):105-9.

(8) Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020; 395(10223):497-506.

(9) Organización Mundial de la Salud. Weekly epidemiological update on COVID-19 - OMS [Internet]. 2021 [citado 4 de octubre de 2022]. Disponible en: https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---28-december-2021

(10) Organización Panamericana de la Salud. Informes de situación de la COVID-19 | OPS/OMS [Internet]. OPS. 2020 [citado 4 de octubre de 2022]. Disponible en: https://www.paho.org/es/informes-situacion-covid-19

(11) Ministerio de Salud Pública y Bienestar Social. Reporte Paraguay COVID-19 [Internet]. MSPBS. 2022 [citado 4 de octubre de 2022]. Disponible en: https://www.mspbs.gov.py/reportes-covid19.html

(12) Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, et al. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. N. Engl. J. Med. 2020;383(27):2603-15.

(13) Baden LR, El Sahly HM, Essink B, Kotloff K, Frey S, Novak R, et al. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N. Engl. J. Med. 2021;384(5):403-16.

(14) Ministerio de Salud Pública y Bienestar Social. Autorizan vacunas contra el COVID-19 en carácter de emergencia [Internet]. MSPBS. 2020 [citado 4 de octubre de 2022]. Disponible en: https://www.mspbs.gov.py/portal/22419/autorizan-vacunas-contra-el-covid-19-en-caracter-de-emergencia.html

(15) Ministerio de Salud Pública y Bienestar Social. Reportes de Vacunados – Programa Ampliado de Inmunizaciones – PAI [Internet]. 2020 [citado 4 de octubre de 2022]. Disponible en: https://pai.mspbs.gov.py/reportes-de-vacunados/

(16) Chodick G, Tene L, Patalon T, Gazit S, Tov AB, Cohen D, et al. The effectiveness of the first dose of BNT162b2 vaccine in reducing SARS-CoV-2 infection 13-24 days after immunization: real-world evidence. medRxiv; 2021;21(01):06-12. Disponible en: https://www.medrxiv.org/content/10.1101/2021.01.27.21250612v1

(17) Bernal JL, Andrews N, Gower C, Stowe J, Robertson C, Tessier E, et al. Early effectiveness of COVID-19 vaccination with BNT162b2 mRNA vaccine and ChAdOx1 adenovirus vector vaccine on symptomatic disease, hospitalisations and mortality in older adults in England. MedRxiv; 2021. Disponible en: https://www.medrxiv.org/content/10.1101/2021.03.01.21252652v1

(18) Vasileiou E, Simpson CR, Robertson C, Shi T, Kerr S, Agrawal U, et al. Effectiveness of First Dose of COVID-19 Vaccines Against Hospital Admissions in Scotland: National Prospective Cohort Study of 5.4 Million People. Rochester, NY; 2021. Disponible en: https://papers.ssrn.com/abstract=3789264

(19) Canlas FQ, Nair S, Paat ID. Exploring COVID-19 Vaccine Side Effects: A Correlational Study Using Python. Procedia Comput. Sci. 2022;201:752-7.

(20) Prakash S. Development of COVID 19 vaccine: A summarized review on global trials, efficacy, and effectiveness on variants. Diabetes Metab. Syndr. Clin. Res. Rev. 2022;16(4):102482.

(21) Bok K, Sitar S, Graham BS, Mascola JR. Accelerated COVID-19 vaccine development: milestones, lessons, and prospects. Immunity. 2021; 54(8):1636-51.

(22) Canadian National Vaccine Safety (CANVAS) Network. Recursos COVID-19 – CANVAS-COVID [Internet]. CANVAS. 2020 [citado 4 de octubre de 2022]. Disponible en: https://canvas-covid.ca/covid-resources/

(23) Maguiña Vargas C, Gastelo Acosta R, Tequen Bernilla A, Maguiña Vargas C, Gastelo Acosta R, Tequen Bernilla A. El nuevo Coronavirus y la pandemia del Covid-19. Rev. Medica Hered. 2020;31(2):125-31.

(24) Rios-González CM, Mendez J, Estigarribia G, Aguilar G, Martínez P, Rios-González CM, et al. Efectos secundarios de las vacunas anti COVID-19 en personal de salud de Paraguay: estudio exploratorio. Rev. Salud Publica Parag. 2021;11(2):24-9.

(25) Aguirre-Morales N, Gómez-Henao C, Calle AM, Cardona-Villa R, Diez-Zuluaga LS, Santamaría-Salazar LC, et al. Reacciones adversas asociadas a vacunas contra la COVID-19. CES Med. 2021;35(3):230-43.

(26) Álvarez Collado L, Castiñeiras Ortega M, González Contreras F, González de Abreu JM, Casma López RM, Núñez López MC, et al. Reacciones adversas notificadas tras la administración de vacuna frente a Covid-19 en trabajadores de un hospital terciario. Rev. Asoc. Esp. Espec. En Med. Trab.. 2021;30(2):217-28.

(27) Saeed BQ, Al-Shahrabi R, Alhaj SS, Alkokhardi ZM, Adrees AO. Side effects and perceptions following Sinopharm COVID-19 vaccination. Int. J. Infect. Dis. 2021;111:219-26.

(28) Zare H, Rezapour H, Mahmoodzadeh S, Fereidouni M. Prevalence of COVID-19 vaccines (Sputnik V, AZD-1222, and Covaxin) side effects among healthcare workers in Birjand city, Iran. Int. Immunopharmacol. 2021; 101:108351.

(29) Castelo-Rivas WP, Ruiz-Ortega JC, Valencia-Pallaroso ML, Castelo-Rivas WP, Ruiz-Ortega JC, Valencia-Pallaroso ML. Manifestaciones clínicas post vacunación con AstraZeneca en docentes de la Unidad Educativa Emilio LorenzoStehle. Rev. Arch. Méd. Camagüey. 2022;26.

(30) Chrissian AA, Oyoyo UE, Patel P, Lawrence Beeson W, Loo LK, Tavakoli S, et al. Impact of COVID-19 vaccine-associated side effects on health care worker absenteeism and future booster vaccination. Vaccine. 2022;40(23):3174-81.

(31) Organización Mundial de la Salud. Efectos secundarios de las vacunas contra la COVID-19 [Internet]. OMS. 2021 [citado 17 de octubre de 2022]. Disponible en: https://www.who.int/es/news-room/feature-stories/detail/side-effects-of-covid-19-vaccines

(32) Ministerio de Salud Pública y Bienestar Social. Efectos adversos más reportados después de la vacunación anticovid [Internet]. MSPBS. 2021 [citado 17 de octubre de 2022]. Disponible en: https://www.mspbs.gov.py/portal/23842/efectos-adversos-mas-reportados-despues-de-la-vacunacion-anticovid.html

Downloads

Published

2023-05-31

Issue

Section

Original Article

How to Cite

1.
Adverse effects associated with COVID-19 vaccines in officials and students of the Faculty of Chemical Sciences of UNA, year 2021. Rev. Soc. cient. Py. [Internet]. 2023 May 31 [cited 2025 Sep. 24];28(1):71-83. Available from: https://sociedadcientifica.org.py/ojs/index.php/rscpy/article/view/304

Similar Articles

1-10 of 111

You may also start an advanced similarity search for this article.